Sermorelin acetate is a synthetic analog of naturally occurring Growth Hormone-Releasing Hormone (GHRH). GHRH is produced in an area of the brain called the hypothalamus from which it is released into blood vessels that carry it to the pituitary gland. Once there, it stimulates production and secretion of growth hormone (GH) which is necessary for growth and development during childhood, as well as for maintenance of normal body composition and metabolism in adults. When GH concentrations are low, deficiency causes poor growth, inadequate muscle and bone development, as well as increased risk for development of intrinsic diseases such as diabetes and other pathologies. Such deficiencies can be opposed by administration of sermorelin which stimulates the pituitary gland to increase output of GH and thereby elevate and restore its serum concentrations to normal levels.
Sermorelin is a synthetic (man-made) version of naturally occurring GHRH that is produced in the brain and can be used clinically to stimulate release of growth hormone (GH) from the pituitary gland. Growth hormone is important in adults to maintain metabolic and physiologic functions that are necessary for good health and quality of life. Thus, Sermorelin can be effective in cases of GH insufficiency and thereby sustain essential bodily functions throughout life
Symptoms of Adult Growth Hormone Deficiency/Insufficiency
Adults with inadequate concentrations of serum GH can have a variety of signs and symptoms, some of which include abnormal body composition, reduced fluid volume, diminished strength, physical energy and stamina, lack of motivation, lethargy, lability etc. Symptoms of growth hormone deficiency also depend on age, and often those meeting the classic definition of adult onset GHD can have different symptoms. However, those with adult-onset GHD that are causally unrelated to aging have similar clinical symptoms as those that occur progressively in incidence and severity with advancing age.